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Years of Experience
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Publications/Book Chapters
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Residents Trained

Castle Connolly
Top Doctors.
America’s Top Doctors, U.S.
News and World Report
Alpha Omega Alpha National Honor Society, USC School of Medicine.
National Honor Society, inducted
Achievement Award,
American Academy of Orthopaedic Surgeons
UCLA President’s
Medal of Honor.

AboutDr. MirzayanDouble-Board Certified
Orthopedic Sports Medicine Surgeon

Dr. Raffy Mirzayan is a double board-certified orthopedic surgeon in Los Angeles with over 25 years of experience providing world-class care to help patients regain motion with confidence and live stronger. Known for his compassionate, patient-centered approach and advanced surgical skill, he specializes in joint preservation—including cartilage restoration—and complex shoulder, elbow, and knee reconstruction. As a leading shoulder and elbow specialist, Dr. Mirzayan is the inventor of Biologic Tuberoplasty*™—a minimally invasive technique that allows patients with massive rotator cuff tears to return to activities like golf, tennis, and pickleball with minimal downtime.

Board Certification

American Board of Orthopaedic Surgery
American Board of Orthopaedic Sports Medicine

State of the Art Orthopedic Care backed by InnovationRegain Strength, Mobility, and Confidence

Dr. Mirzayan offers advanced, innovative, state of the art treatments to maximize patient outcomes

Joint Preservation

Advancing joint preservation through orthobiologics and cartilage restoration
Shoulder
Elbow
Knee

0 Cartilage Transplantations
0 Rotator Cuff Repairs
0 Elbow Arthroscopies
0 Tommy John
0 Biceps/Triceps Repairs
0 OCD Capitellum

Active Member of
Following Professional Societies

What Our Patients Are SayingReal Stories, Real Results

I give Dr Mirzayan my highest recommendation! I am a primary care sports medicine physician and I have worked with many orthopedic surgeons in the past. I chose Dr Mirzayan over other orthopedic surgeons for my ACL reconstruction based on his stellar reputation. He far exceeded my expectations. Not ...-J T -
Dr. Raffy Mirzayan is a skilled, knowledgeable, kind and understanding surgeon. He did a reverse shoulder replacement for me and I look forward to full use of my arm. I would highly recommend Dr. Mirzayan, he is a master surgeon.-T S -
Dr Mirzayan is the BEST had Knee surgery in my early 40s with no problems, can kick a soccer ball,now in my 60s Doc did my shoulder,Torn Rotary Cuff and feeling good,Dr Mirzayan has kept me in good shape,to where I can walk with No pain,and still able to do upper body exercises Thank you Doc.-R C -

Areas of ExpertiseLeading the Way in Orthopedic Innovation

MINIMALLY INVASIVE SURGERYBiologic Tuberoplasty

Dr. Mirzayan is the inventor of *Biologic Tuberoplasty*™, a minimally invasive, arthroscopic procedure where donated human skin is attached to the top of the ball of the ball and socket joint in patients with massive, irreparable rotator cuff tears and who may have been told they need a reverse shoulder replacement. The procedure is a same day surgery, lasts about 1 hour and patients can be back to sports relatively quickly with minimal downtime

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Advanced TechniquesCartilage Transplantation & BioPFJ™

Dr. Mirzayan is one of the most experienced cartilage restoration surgeons in the United States, having performed over 350 cartilage transplantation procedures in the knee, shoulder, and elbow. When cartilage is damaged or missing, the joint loses its natural cushioning — leading to pain, swelling, and eventually arthritis.

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CUTTING-EDGE TECHNOLOGYScarless Needle Arthroscopy

The procedure that uses a tiny camera inserted through a needle-sized incision to diagnose and treat joint problems. It allows real-time visualization, faster recovery, less pain, and often avoids traditional surgery while providing accurate, in-office assessment for patients with knee, shoulder, or ankle symptoms today.

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NONSURGICAL TREATMENTSPlatelet-Rich Plasma (PRP) and Bone Marrow Cells

The treatment involves use of the patient’s own concentrated platelets to promote healing in injured or arthritic tissues. Rich in growth factors, PRP may reduce pain, improve function, and support tissue repair in joints, tendons, and ligaments, often helping delay or avoid surgery.

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FEATURED INSIGHTSMedia Interviews

How innovative fresh osteochondral allografts in orthopedics affect patient care. Becker’s ASC Review by Laura Dyrda January 25, 2016
“In the Lab: Advances in Knee Surgery.”
By Karen Ravn, Los Angeles Times, 3/12/07
“High Speed Healing.”
by Matt Bean, Men’s Health Magazine, 10/06
“What the Knee Needs.”
by Chana R. Schoenberger, Forbes Magazine, 11/13/06
“Your Knees: Care and Maintenance.”
by Nick Heil, Outside Magazine, 9/06

EXPERT ORTHOPEDIC PERSPECTIVESPodcast

Professional discussions on surgical techniques, outcomes research, and evolving standards in orthopedic care.

"Is There a Hamstring Autograft Diameter Threshold for Anterior Cruciate Ligament Reconstruction?" with Author Dr. Raffy Mirzayan
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Hosted by Dr. Scott Sigman – “Dr. Raffy Mirzayan”
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AJSM August 2024 Podcast: Fresh Osteochondral Allograft Transplantation of the Capitellum for the Treatment of Osteochondritis Dissecans
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ASES Podcast - Episode 123 - Capitellar Osteochondral Defects
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AJSM November 2017 Podcast: Surgical Treatment of Distal Biceps Tendon Ruptures: An Analysis of Complications in 784 Surgical Repairs
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RESEARCH & INSIGHTSResearch & Publications

Fresh Osteochondral Allograft Transplantation of the Capitellum for the Treatment of Osteochondritis Dissecans.
Is There a Hamstring Autograft Diameter Threshold for Anterior Cruciate Ligament Reconstruction?
Patients with Graft Tears Leaving the Tuberosity Covered Have Similar Functional Outcomes as Those with an Intact Graft Following Superior Capsule Reconstruction.